No evidence of dermal sensitization in human or animal testing.
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low
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A. Lapczynski, S. Tsang, Y. Tokura, Y. Thakkar, G. Sullivan, I. G. Sipes, T. W. Schultz, D. Salvito, N. Sadekar, J. Romine, G. Ritacco, T. M. Penning, A. Patel, D. O'Brien, D. C. Liebler, A. M. Api, S. La Cava, K. Joshi, L. Jones, A. D. Fryer, M. Francis, C. Deodhar, W. Dekant, M. Date, M. L. Dagli, J. Buschmann, G. A. Burton, M. Bruze, D. Botelho & D. Belsito. 2018. RIFM fragrance ingredient safety assessment, ethyl 2-methyl-1,3-dioxolane-2-acetate, CAS Registry Number 6413-10-1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 122 Suppl 1, S438-S444.
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No evidence of genotoxicity in limited in vitro tests.
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low
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A. Lapczynski, S. Tsang, Y. Tokura, Y. Thakkar, G. Sullivan, I. G. Sipes, T. W. Schultz, D. Salvito, N. Sadekar, J. Romine, G. Ritacco, T. M. Penning, A. Patel, D. O'Brien, D. C. Liebler, A. M. Api, S. La Cava, K. Joshi, L. Jones, A. D. Fryer, M. Francis, C. Deodhar, W. Dekant, M. Date, M. L. Dagli, J. Buschmann, G. A. Burton, M. Bruze, D. Botelho & D. Belsito. 2018. RIFM fragrance ingredient safety assessment, ethyl 2-methyl-1,3-dioxolane-2-acetate, CAS Registry Number 6413-10-1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 122 Suppl 1, S438-S444.
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