Health issue
Level of Concern
Source
A Cosmetic ingredient Review safety assessment noted cocamidopropylamine oxide has an acute oral toxicity LD50 as low as 500 mg/kg body weight.
some
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
A Cosmetic ingredient Review safety assessment found that cocamidopropylamine oxide is not a skin irritant at concentrations relevant to cleaners.
low
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
A Cosmetic ingredient Review safety assessment noted cocamidopropylamine oxide has an acute dermal toxicity LD50 greater than 2174 mg/kg body weight.
low
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
A Cosmetic ingredient Review safety assessment found that cocamidopropylamine oxide is not a skin sensitizer.
low
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
This chemical has been verified to be of low concern in cleaning products based on experimental and modeled data as assessed by the EPA.
low
Environmental Protection Agency (EPA): Safer Chemical Ingredients List (2018-02-28)
A Cosmetic ingredient Review safety assessment found that cocamidopropylamine oxide did not cause mutations in cell studies.
low
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
Health issue
Level of Concern
Source
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes severe skin burns and eye damage
Only in: Oven Cleaner; Drain Opener/Clog Remover; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Harmful if swallowed
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
May cause an allergic skin reaction
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes severe skin burns and eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Harmful in contact with skin
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
may cause respiratory irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
NTP Toxcast scored 1.5-2.5
some
National Toxicology Program (NTP): EWG Toxcast Analysis
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes serious eye damage
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Not known to cause asthma
low
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)