developmentb
C

COCAMIDOPROPYLAMINE OXIDE

 

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation.

This substance ranges from B to C depending on concentration/usage.

Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Low Concern
 
Developmental &
Reproductive Toxicity
 
No Data, Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: No information available on this substance.
COCAMIDOPROPYLAMINE OXIDE can be found in 44 products.
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Evidence

Health issue
 
Level of Concern
 
Source
A Cosmetic ingredient Review safety assessment noted cocamidopropylamine oxide has an acute oral toxicity LD50 as low as 500 mg/kg body weight.
 
some
 
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
A Cosmetic ingredient Review safety assessment found that cocamidopropylamine oxide is not a skin irritant at concentrations relevant to cleaners.
 
low
 
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
A Cosmetic ingredient Review safety assessment noted cocamidopropylamine oxide has an acute dermal toxicity LD50 greater than 2174 mg/kg body weight.
 
low
 
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
A Cosmetic ingredient Review safety assessment found that cocamidopropylamine oxide is not a skin sensitizer.
 
low
 
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.
This chemical has been verified to be of low concern in cleaning products based on experimental and modeled data as assessed by the EPA.
 
low
 
Environmental Protection Agency (EPA): Safer Chemical Ingredients List (2018-02-28)
A Cosmetic ingredient Review safety assessment found that cocamidopropylamine oxide did not cause mutations in cell studies.
 
low
 
2008. Amended final report of the safety assessment of cocamidopropylamine oxide. International journal of toxicology 27 Suppl 1, 55-62.

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes severe skin burns and eye damage
Only in: Oven Cleaner; Drain Opener/Clog Remover; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Harmful if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes severe skin burns and eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Harmful in contact with skin
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
may cause respiratory irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
NTP Toxcast scored 1.5-2.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes serious eye damage
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Not known to cause asthma
 
low
 
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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