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The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
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high
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Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
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The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
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high
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Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
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A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
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some
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Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
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The CIR panel reports equivocal evidence that tocopherol may act as a tumor promoter.
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some
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Cosmetic Ingredient Review (CIR): CIR Assessments
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May cause an allergic skin reaction
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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May cause an allergic skin reaction
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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The CIR panel reports that tocopherol was a dermal sensitizer in an animal study and contact allergy has been reported in human tests and case studies, although occurrence is rare.
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some
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Cosmetic Ingredient Review (CIR): CIR Assessments
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Tocopherol functions as an antioxidant in personal care products.
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low
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Cosmetic Ingredient Review (CIR): CIR Assessments
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Tocopherol was not genotoxic in in vitro tests with mammalian cells.
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low
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Cosmetic Ingredient Review (CIR): CIR Assessments
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A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
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low
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Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
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This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
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low
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U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
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