May cause genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May cause cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity (to females)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity (to males)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Known To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Reasonably Anticipated To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes pulmonary edema
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes skin corrosion
Only in: Oven Cleaner; Drain Opener/Clog Remover
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes reproductive effects
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes leukemia
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes peritoneal cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
cancer
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
central nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
Asthmagen (irritation)
|
some
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
Causes cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
liver damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
suspected human carcinogen
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
Possibly carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Renal failure occurred in an adult man who ingested dipropylene glycol .
|
some
|
Frank LoVecchio, Cameron Nourani, D. J. Watts, K. L. Wallance & P. M. Wax. 2008. Acute renal failure, neuropathy, and myopathy after ingestion of dipropylene glycol fog solution. The American journal of emergency medicine 26(5), 635.e1-2.
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Effects on kidneys observed at high doses in chronic toxicity study in rats.
|
some
|
2004. NTP toxicology and carcinogensis studies of dipropylene glycol (CAS No. 25265-71-8) in F344/N rats and B6C3F1 mice (drinking water studies). National Toxicology Program technical report series(511), 6-260.
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes eye corrosion
Only in: Drain Opener/Clog Remover; Oven Cleaner
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Contact dermatitis was rarely observed in a human patch test study with 500 participants.
|
some
|
J. D. Johansen, G. B. Jemec & S. C. Rastogi. 1995. Contact sensitization to dipropylene glycol in an eczema population. Contact dermatitis 33(3), 211-2.
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Mild skin irritant in animal tests.
|
some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Eye irritant in animal tests.
|
low
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
acute toxicity, dermal LD50 (mg/kg)
|
low
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
Low acute oral toxicity.
|
low
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
No evidence of cancer in chronic high dose animal study
|
low
|
Michelle J. Hooth, Ronald A. Herbert, Joseph K. Haseman, Denise P. Orzech, Jerry D. Johnson & John R. Bucher. 2004. Toxicology and carcinogenesis studies of dipropylene glycol in rats and mice. Toxicology 204(2-3), 123-40.
|
No reproductive or developmental toxicity observed in animal studies.
|
low
|
Jeff R. Fowles, Marcy I. Banton & Lynn H. Pottenger. 2013. A toxicological review of the propylene glycols. Critical reviews in toxicology 43(4), 363-90.
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
|
EPA testing shows this substance has low acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
Only in: Household Cleaners
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
The European Union Ecolabel program reports this substance is readily biodegradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|