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Data: Limited

Isopropyl Alcohol

IMAGE SOURCE: PubChem

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Other Concerns

Non-reproductive organ system toxicity (low_moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (low_moderate)

SYNONYMS

● 2-PROPANOL, SEMICONDUCTOR GRADE MOS PURANAL(TM) (HONEYWELL 17930)
● ISOPROPYL ALCOHOL, EUROPEPHARMACOPOEIA (EP) REFERENCE STANDARD
● 2-PROPANOL, SEMICONDUCTOR GRADE SLSI PURANAL(TM) (HONEYWELL 17030)
● ISOPROPYL ALCOHOL, MEETS EP, BP, USP TESTING SPECIFICATIONS
● 2-PROPANOL, UNITED STATES PHARMACOPEIA (USP) REFERENCE STANDARD
● 2-PROPANOL, PURISS., MEETS ANALYTICAL SPECIFICATION OF PH. EUR., BP, USP, >=99.5% (GC)
● 2-PROPANOL, >=99.7%, SUITABLE FOR ABSORPTION SPECTRUM ANALYSIS
● 2-PROPANOL, HPLC PLUS, FOR HPLC, GC, AND RESIDUE ANALYSIS, 99.9%
● 2-PROPANOL, >=99.7%, FOR RESIDUE ANALYSIS, SUITABLE FOR 1000 PER JIS
● 2-PROPANOL, PHARMACEUTICAL SECONDARY STANDARD; CERTIFIED REFERENCE MATERIAL

This ingredient is not currently on EWG's Skin Deep Restricted or Unacceptable Lists.

Isopropyl alcohol is a common solvent.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
nail treatment110 products
exfoliant/scrub19 products
mask113 products
conditioner903 products
shampoo159 products
muscle/joint soreness2 products
vapor rubs1 products
nail polish2903 products
facial cleanser20 products
hair spray29 products
hair treatment/serum270 products
styling gel/lotion37 products
polish remover10 products
mascara38 products
toners/astringents11 products
after shave9 products
hair relaxer2 products
hair styling aid107 products
detangler18 products
hand sanitizer126 products
hair color and bleaching293 products
moisturizer36 products
eye makeup remover1 products
facial moisturizer/treatment17 products
Other Hair Care Preparations2 products
body firming lotion11 products
styling mousse/foam12 products
bronzer/highlighter1 products
body oil6 products
Hair Styling Gel1 products
blush1 products
nail glue181 products
damaged skin treatment4 products
makeup primer4 products
serums & essences15 products
makeup remover3 products
foot moisturizer7 products
body spray1 products
foundation49 products
foot cleansing5 products
after sun product8 products
body wash/cleanser16 products
hand cream4 products
beard care2 products
eye liner3 products
antiperspirant/deodorant2 products
lip gloss29 products
beard cleanser2 products
lip balm1 products
brow liner3 products
Bath and Body Wipes2 products
CC cream1 products
hair-loss treatment3 products
Basecoats and Undercoats3 products
BB cream5 products
daily use with SPF1 products
setting powder/spray1 products
bath oil/salts/soak44 products
liquid hand soap2 products
toothpaste1 products
anti-aging2 products
around-eye cream3 products
bar soap3 products
eyelash glue4 products
shaving cream7 products
shaving cream (men's)1 products
concealer2 products
skin fading/lightener1 products
bubble bath2 products
foot odor control1 products
lip liner1 products
baby shampoo1 products
baby soap1 products
acne treatment1 products
Nail Art and Jewelry2 products
Face Wipes1 products
Massaging Preparations1 products
Top Coats and Sealers7 products
Nail Creams and Lotions1 products
Facial Cleansing Water1 products

Occupational hazards

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CONCERN REFERENCE
Moderate evidence of occupational hazards[Industrial bronchitis in workers exposed to hydroalcohol](2007-11-01)
Limited evidence of occupational hazardsToxicity of isopropyl alcohol exposure on the nasal mucociliary system in the guinea pig(1988-06-01)

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Associated with systemic toxicityIsopropyl alcohol intoxication: a diagnostic challenge(2002-09-01)
Associated with respiratory toxicityRespiratory failure, lung infiltrates, and hemoptysis in a woman with chronic isopropyl alcohol inhalation(2012-06-01)
Classified as toxic or harmful.Absorption of topical isopropyl alcohol in an adult(1989-11-01)
Classified as expected to be toxic or harmfulEnvironment Canada
Classified as medium human health priorityEnvironment Canada
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)Environmental Protection Agency (EPA)

Allergies/immunotoxicity

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CONCERN REFERENCE
Limited evidence of skin toxicity or allergiesAllergic contact dermatitis caused by isopropyl alcohol: a missed allergen?(2011-08-01)

Enhanced skin absorption

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CONCERN REFERENCE
Penetration enhancerRole of isopropyl myristate, isopropyl alcohol and a combination of both in hydrocortisone permeation across the human stratum corneum(1900-01-01)
Penetration enhancerAcute effects of isopropyl alcohol exposure on the middle ear mucosa(1987-06-01)

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Classified as eye irritantEU GHS Hazard Labeling Codes
Classified as any irritantEU GHS Hazard Labeling Codes

Cancer

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CONCERN REFERENCE
Not likely to be carcinogenic in humansInternational Agency for Research on Cancer (IARC)

Miscellaneous

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CONCERN REFERENCE
Occupational hazards related to handlingEU GHS Hazard Labeling Codes

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported 'as used' concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review (CIR)

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review (CIR)

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodUS Food and Drug Administration (FDA)

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada

Neurotoxicity

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CONCERN REFERENCE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyUS National Library of Medicine,
  • [Industrial bronchitis in workers exposed to hydroalcohol](2007-11-01)
  • Toxicity of isopropyl alcohol exposure on the nasal mucociliary system in the guinea pig(1988-06-01)
  • Isopropyl alcohol intoxication: a diagnostic challenge(2002-09-01)
  • Respiratory failure, lung infiltrates, and hemoptysis in a woman with chronic isopropyl alcohol inhalation(2012-06-01)
  • Absorption of topical isopropyl alcohol in an adult(1989-11-01)
  • Environment Canada
  • Environmental Protection Agency (EPA)
  • Allergic contact dermatitis caused by isopropyl alcohol: a missed allergen?(2011-08-01)
  • Role of isopropyl myristate, isopropyl alcohol and a combination of both in hydrocortisone permeation across the human stratum corneum(1900-01-01)
  • Acute effects of isopropyl alcohol exposure on the middle ear mucosa(1987-06-01)
  • EU GHS Hazard Labeling Codes
  • International Agency for Research on Cancer (IARC)
  • Cosmetic Ingredient Review (CIR)
  • US Food and Drug Administration (FDA)
  • US National Library of Medicine,

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.


HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG Verified® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend
WEIGHT-OF-EVIDENCE APPROACH

A product’s hazard score is not an average of the ingredients’ hazard scores. It is calculated using a weight-of-evidence approach that factors in all of the hazards or health impacts associated with the ingredients.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability
NONE

Ingredients have not been assessed.

LIMITED-FAIR

There is only a modest volume of research.

GOOD-ROBUST

Ingredients have been studied extensively.

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