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Data: Limited

Sh Oligopeptide 1

Other Concerns

Enhanced skin absorption

SYNONYMS

● EPIDERMAL GROWTH FACTOR
● UROGASTRONE
● UROGASTRON
● UROENTERONE
● UROANTHELONE
● EPIDERMAL GROWTH FACTOR (EGF)
● KUTROL
● GASTRONE, URO- (9CI)
● EGF
● ANTHELONE U

This ingredient is not currently on EWG's Skin Deep Restricted or Unacceptable Lists.


sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
anti-aging3 products
facial moisturizer/treatment11 products
moisturizer3 products
around-eye cream3 products
serums & essences18 products
lip balm1 products
mask5 products
daily use with SPF2 products
acne treatment1 products
nail treatment1 products
body wash/cleanser1 products

Cancer

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CONCERN REFERENCE
One or more in vitro tests on mammalian cells show positive mutation resultsRole of epidermal growth factor in carcinogenesis(1986-03-01)
Not likely to be carcinogenic in humansEpidermal growth factor in clinical practice - a review of its biological actions, clinical indications and safety implications(2009-10-01)
  • Role of epidermal growth factor in carcinogenesis(1986-03-01)
  • Epidermal growth factor in clinical practice - a review of its biological actions, clinical indications and safety implications(2009-10-01)

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.


HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG Verified® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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