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Data: Limited

Cannabis Sativa Flower/Leaf/Stem Extract

  • Products with this ingredient are allowed for use in EWG VERIFIED but must meet use restrictions and warnings based on EWG review of company data.
  • This ingredient's score is higher if used in products that may not meet industry safety guidelines or U.S. and international government requirements and may have contamination concerns from toxic impurities. The score will be lower if used in products that do meet these safety guidelines and requirements and EWG’s contamination restrictions.

Other Concerns

Use restrictions (high), Neurotoxicity (low), Endocrine disruption (low), Non-reproductive organ system toxicity (low), Irritation (skin, eyes, or lungs) (low), and Contamination concerns (high)

SYNONYMS

● CANNABIS SATIVA FLOWER/LEAF/STEM EXTRACT

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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facial moisturizer/treatment11 products
bath oil/salts/soak4 products
serums & essences4 products
moisturizer6 products
muscle/joint soreness3 products
anti-aging1 products
body firming lotion1 products
body oil5 products
lip balm2 products
after shave1 products
around-eye cream2 products
after sun product1 products
hand sanitizer1 products
mask2 products
bar soap1 products
exfoliant/scrub3 products
shaving cream (men's)1 products

Contamination concerns

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Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Limited evidence of liver toxicityHepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model(2019-04-01)
Classified as toxic or harmful.European Chemicals Agency (ECHA)

Neurotoxicity

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CONCERN REFERENCE
One or more animal studies show effects at moderate dosesCannabis-induced impairment of learning and memory: effect of different nootropic drugs(2013-01-01)
One or more animal studies show neurological effects at moderate dosesOcular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol(1984-01-01)

Developmental/reproductive toxicity

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CONCERN REFERENCE
One or more animal studies show male reproductive system effects at moderate dosesTesticular toxicity in cannabis extract treated mice: association with oxidative stress and role of antioxidant enzyme systems(2010-02-01)
One or more animal studies show developmental effects at moderate dosesEffect of marihuana extract on fetal hamsters and rabbits(1969-03-01)

Endocrine disruption

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CONCERN REFERENCE
One or more animal studies show endocrine disruption at moderate dosesEffect of treatment with cannabis extract on the water and glycogen contents of the uterus in normal and estradiol-treated prepubertal rats(1975-12-01)
Associated with endocrine disruptionMarijuana extracts possess the effects like the endocrine disrupting chemicals(2005-01-01)

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
One or more animal studies show eye irritation at moderate dosesOcular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol(1984-01-01)
Limited evidence of eye irritationEuropean Chemicals Agency (ECHA)
Limited evidence of skin irritationEuropean Chemicals Agency (ECHA)

Ecotoxicology

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CONCERN REFERENCE
Limited evidence of environmental toxicityEuropean Chemicals Agency (ECHA)

Allergies/immunotoxicity

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CONCERN REFERENCE
Limited evidence of skin toxicity or allergiesEuropean Chemicals Agency (ECHA)

Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Banned or found unsafe for use in cosmeticsEU Cosmetics Directive
  • Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model(2019-04-01)
  • European Chemicals Agency (ECHA)
  • Cannabis-induced impairment of learning and memory: effect of different nootropic drugs(2013-01-01)
  • Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol(1984-01-01)
  • Testicular toxicity in cannabis extract treated mice: association with oxidative stress and role of antioxidant enzyme systems(2010-02-01)
  • Effect of marihuana extract on fetal hamsters and rabbits(1969-03-01)
  • Effect of treatment with cannabis extract on the water and glycogen contents of the uterus in normal and estradiol-treated prepubertal rats(1975-12-01)
  • Marijuana extracts possess the effects like the endocrine disrupting chemicals(2005-01-01)
  • EU Cosmetics Directive

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.


HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG Verified® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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