Evidence
Health issue
Level of Concern
Source
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has an acute dermal LD50 of 200 mg/kg body weight in rabbits.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has an acute dermal LD50 of 200 mg/kg body weight in rabbits.
moderate
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium decyl sulfate has an acute oral LD50 of 290 mg/kg body weight.
The international Organisation for Economoic Co-operation and Development reported that sodium decyl sulfate has an acute oral LD50 of 290 mg/kg body weight.
moderate
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has an acute oral LD50 of 1,200 mg/kg body weight in rats.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has an acute oral LD50 of 1,200 mg/kg body weight in rats.
some
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has a chronic aquatic toxicity NOEC of 2 mg/L.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has a chronic aquatic toxicity NOEC of 2 mg/L.
some
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that C14-16 alpha-olefin sulfonate has an acute oral LD50 of 578 mg/kg body weight.
The international Organisation for Economoic Co-operation and Development reported that C14-16 alpha-olefin sulfonate has an acute oral LD50 of 578 mg/kg body weight.
some
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development noted repeated dermal exposure to at least 10 percent of C12-15 alkyl sulfates can cause dermal hyperplasia in mice.
The international Organisation for Economoic Co-operation and Development noted repeated dermal exposure to at least 10 percent of C12-15 alkyl sulfates can cause dermal hyperplasia in mice.
some
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that C14-16 alpha-olefin sulfonates has moderate aquatic toxicity to fish
The international Organisation for Economoic Co-operation and Development concluded that C14-16 alpha-olefin sulfonates has moderate aquatic toxicity to fish
some
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
European Union Ecolabel program data shows this substance has high acute toxicity to aquatic life
European Union Ecolabel program data shows this substance has high acute toxicity to aquatic life
some
EU Ecolabel: Detergents Ingredients Database
Alkyl Sulfates
European Union Ecolabel program data shows this substance has moderate chronic toxicity to aquatic life
European Union Ecolabel program data shows this substance has moderate chronic toxicity to aquatic life
some
EU Ecolabel: Detergents Ingredients Database
Alkyl Sulfates
Harmful if swallowed
Only in: Household Cleaners
Harmful if swallowed
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Alkyl Sulfates
harmful in inhaled
Only in: Household Cleaners
harmful in inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that C12-16 alkyl sulfates can irritate skin at concentrations above 5 percent.
The international Organisation for Economoic Co-operation and Development reported that C12-16 alkyl sulfates can irritate skin at concentrations above 5 percent.
some
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
may cause respiratory irritation
Only in: Household Cleaners
may cause respiratory irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Alkyl Sulfates
Causes serious eye damage
Only in: Household Cleaners
Causes serious eye damage
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Alkyl Sulfates
Causes skin irritation
Only in: Household Cleaners
Causes skin irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that C12-18 alkyl sulfates have acute oral LD50s of greater than 2000 mg/kg body weight.
The international Organisation for Economoic Co-operation and Development reported that C12-18 alkyl sulfates have acute oral LD50s of greater than 2000 mg/kg body weight.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not skin sensitizers.
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not skin sensitizers.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that alkyl sulfonates have moderate acute aquatic toxicity to Daphnia.
The international Organisation for Economoic Co-operation and Development reported that alkyl sulfonates have moderate acute aquatic toxicity to Daphnia.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
This chemical has been verified to be of low concern in cleaning products based on experimental and modeled data as assessed by the EPA.
This chemical has been verified to be of low concern in cleaning products based on experimental and modeled data as assessed by the EPA.
low
Environmental Protection Agency (EPA): Safer Chemical Ingredients List (2018-02-28)
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate is not genotoxic.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate is not genotoxic.
low
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate is readily biodegradable.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate is readily biodegradable.
low
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has a low bioconcentration factor.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has a low bioconcentration factor.
low
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has a high NOAEL for developmental effects.
The international Organisation for Economoic Co-operation and Development reported that sodium lauryl sulfate has a high NOAEL for developmental effects.
low
Organisation for Economic Co-Operation and Development. 1995. Sodium dodecyl sulfate CAS No. 151-21-3. SIDS Initial Assessment Profile for SIAM 5 October 28-30, 1995.
Alkyl Sulfates
The European Union Ecolabel program reports this substance is readily biodegradable.
The European Union Ecolabel program reports this substance is readily biodegradable.
low
EU Ecolabel: Detergents Ingredients Database
Alkyl Sulfates
The European Union Ecolabel program reports this substance is anaerobically degradable.
The European Union Ecolabel program reports this substance is anaerobically degradable.
low
EU Ecolabel: Detergents Ingredients Database
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not mutagenic.
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not mutagenic.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not carcinogenic.
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not carcinogenic.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that alpha-olefin sulfonates are not toxic to reproduction.
The international Organisation for Economoic Co-operation and Development concluded that alpha-olefin sulfonates are not toxic to reproduction.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that sodium lauryl sulfate has low toxicity to male reproduction.
The international Organisation for Economoic Co-operation and Development concluded that sodium lauryl sulfate has low toxicity to male reproduction.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not developmental toxicants.
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are not developmental toxicants.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.
Alkyl Sulfates
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are readily biodegradable.
The international Organisation for Economoic Co-operation and Development concluded that alkyl sulfates and sulfonates and alpha-olefin sulfonates are readily biodegradable.
low
Organisation for Economic Co-Operation and Development. 2007. Alkyl Sulfates, Alkane Sulfonates, Alpha-Olefin Sulfonates. SIDS Initial Assessment Report for SIAM 25 October 16-19, 2007.