A structurally similar compound is know to be an asthmagen (sensitizing).
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moderate
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2020. Environmental Working Group. 2020. Quaternary ammonium compounds structural similarities.
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fatal if inhaled
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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Toxic of swallowed
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
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some
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Vanessa E. Melin, Travis E. Melin, Brian J. Dessify, Christina T. Nguyen, Caroline S. Shea & Terry C. Hrubec. 2015. Quaternary Ammonium Disinfectants Cause Subfertility in Mice by Targeting both Male and Female Reproductive Processes. Reproductive toxicology (Elmsford, N.Y.).
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A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
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some
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Vanessa E. Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70.
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Harmful if swallowed
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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Quaternary ammonium compounds detected in human blood was associated with increased inflammation, decreased mitochondrial function and disruption of cholesterol.
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some
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Terry C. Hrubec, Ryan P. Seguin, Libin Xu, Gino A. Cortopassi, Sandipan Datta, Alexandra L. Hanlon, Alicia J. Lozano, Valerie A. McDonald, Claire A. Healy, Tyler C. Anderson, Najaha A. Musse & Richard T. Williams. 2021. Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure. Toxicology reports 8, 646-656.
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may cause respiratory irritation
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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Causes serious eye damage
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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Causes skin irritation
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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causes serious eye irritation
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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This substance impacted cholesterol biosynthesis.
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some
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Josi Herron, Rosalyn C. Reese, Keri A. Tallman, Rohini Narayanaswamy, Ned A. Porter & Libin Xu. 2016. Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis. Toxicological sciences : an official journal of the Society of Toxicology 151(2), 261-70.
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Quaternary ammonium compounds altered neurodevelopment in cells.
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some
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Josi M. Herron, Hideaki Tomita, Collin C. White, Terrance J. Kavanagh & Libin Xu. 2021. Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment. Chemical research in toxicology 34(5), 1265-1274.
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This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
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low
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U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
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