Per- and polyfluorinated chemicals (PFAS) are highly persistent in the environment, and humans are widely exposed to PFAS through the environment.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to immunotoxicity in humans and animals.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) are highly persistent in the environment, and humans are widely exposed to PFAS through the environment.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to immunotoxicity in humans and animals.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to reproductive and developmental toxicity in humans and animals.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to cancer in humans and animals
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to cardiovascular effects in humans and animals
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to thyroid disruption in humans and animals.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to reproductive and developmental toxicity in humans and animals.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to cancer in humans and animals
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to cardiovascular effects in humans and animals
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to thyroid disruption in humans and animals.
|
high
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
This substance is a PFAS, which is a chemical class of concern.
|
moderate
|
Carol F. Kwiatkowski, David Q. Andrews, Linda S. Birnbaum, Thomas A. Bruton, Jamie C. DeWitt, Detlef R. U. Knappe, Maricel V Maffini, Mark F. Miller, Katherine E. Pelch, Anna Reade, Anna Soehl, Xenia Trier, Marta Venier, Charlotte C. Wagner, Zhanyun Wang & Arlene Blum. 2020. Scientific Basis for Managing PFAS as a Chemical Class. Environmental science & technology letters 7(8), 532-543.
|
May cause genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May cause cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity (to females)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity (to males)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Known To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Per- and polyfluorinated chemicals (PFAS) have been linked to liver effects in humans and animals
|
some
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Per- and polyfluorinated chemicals (PFAS) have been linked to liver effects in humans and animals
|
some
|
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological Profile for Perfluoroalkyls.
|
Reasonably Anticipated To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes pulmonary edema
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes skin corrosion
Only in: Oven Cleaner; Drain Opener/Clog Remover
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes reproductive effects
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes leukemia
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes peritoneal cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
cancer
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
central nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
Asthmagen (irritation)
|
some
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
Causes cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
liver damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
suspected human carcinogen
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
Possibly carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Organohalogen compounds are often found to be persistent in the environment, bioaccumulative, and associated with chronic health concerns
|
some
|
Prasada Rao S. Kodavanti & Bommanna G. Loganathan. 2017. Organohalogen Pollutants and Human Health. International Encyclopedia of Public Health, 359-366.
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes eye corrosion
Only in: Drain Opener/Clog Remover; Oven Cleaner
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
|
EPA testing shows this substance has low acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|