EWG's Guide to Healthy Cleaning | AZADIRACHTA INDICA LEAF EXTRACT

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HOME / INGREDIENTS / Azadirachta indica leaf extract

AZADIRACHTA INDICA LEAF EXTRACT

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COMMONLY FOUND IN

SYNONYMS

MELIA AZEDARACH, EXT., NEEM (MELIA AZADIRACHTA) LEAF EXTRACT, NEEM LEAF EXTRACT, EXTRACT OF NEEM LEAF, EXTRACT OF MELIA AZADIRACHTA LEAF, BAKAIN STEM BARK EXTRACT, MELIA AZADIRACHTA LEAF EXTRACT, MELIA AZADIRACHTA (NEEM)LEAF EXTRACT, AZADIRACHTA INDICA LEAF EXTRACT

Common Concerns

See how this product scores for common concerns.

No Data

Asthma / Respiratory
No Data

Skin Allergies & Irritation
SOME

Developmental & Reproductive Toxicity
No Data

Cancer
No Data

Environment

Top Scoring Factors

Evidence of developmental/endocrine/reproductive effects; damage to DNA; chronic aquatic toxicity

Ingredient concerns

CONCERNS

Health Issue	Level of Concern	Source

A review article reports this substance is used in traditional medicine as an anti-fertility drug, with evidence of efficacy from animal studies. Thus, it can be considered a reproductive toxin.	some	Shail K. Chaube, Tulsidas G. Shrivastav, Meenakshi Tiwari, Shilpa Prasad, Anima Tripathi & Ajai K. Pandey. 2014. Neem (Azadirachta indica L.) leaf extract deteriorates oocyte quality by inducing ROS-mediated apoptosis in mammals. SpringerPlus 3, 464.
A peer-reviewed study reports that this substance disrupts thyroid hormone physiology in mice.	some	S. Panda & A. Kar. 2000. How safe is neem extract with respect to thyroid function in male mice?. Pharmacological research 41(4), 419-22.
A peer-reviewed study found that this substance was genotoxic to sperm in mice.	some	K. S. Awasthy. 2001. Genotoxicity of a crude leaf extract of neem in male germ cells of mice. Cytobios 106 Suppl 2, 151-64.
Harmful to aquatic life with long lasting effects	low	EU GHS Hazard Labeling Codes: GHS Hazard Codes

Understanding scores

EWG provides information on cleaning product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.

HOW WE DETERMINE SCORES

Hazard score

The Healthy Cleaning ingredient hazard score, from A to F, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED^® mark means a product meets EWG’s strictest criteria for transparency and health.