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HOME / INGREDIENTS / Glycyrrhiza glabra (licorice) root extract (glabridin flavone)


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GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT (Glabridin Flavone)

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SYNONYMS

GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT (NO GLYCYRRHIZINIC ACID), GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT (GLABRIDIN FLAVONE)

Common Concerns

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  • No Data
    Asthma / Respiratory
  • No Data
    Skin Allergies & Irritation
  • No Data
    Developmental & Reproductive Toxicity
  • No Data
    Cancer
  • No Data
    Environment


Top Scoring Factors

No information available on this substance.


Ingredient concerns

  • CONCERNS
Health Issue Level of Concern Source
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Licorice and its constituents/derivatives affect the cardiovascular system by disrupting hormones involved in water/salt balance.

some

Mikkel R. Deutch, Daniela Grimm, Markus Wehland, Manfred Infanger & Marcus Krüger. 2019. Bioactive Candy: Effects of Licorice on the Cardiovascular System. Foods (Basel, Switzerland) 8(10).

Licorice derivatives have exhibited neuroprotective, sedative, and antidepressant effects in various studies, indicating a capacity to elicit nervous system effects.

some

Giulia Pastorino, Laura Cornara, Sónia Soares, Francisca Rodrigues & M. Beatriz P. P. Oliveira. 2018. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytotherapy research : PTR 32(12), 2323-2339.

Licorice and its constituents/derivatives can impact immune function.

some

Giulia Pastorino, Laura Cornara, Sónia Soares, Francisca Rodrigues & M. Beatriz P. P. Oliveira. 2018. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytotherapy research : PTR 32(12), 2323-2339.

Anti-androgenic effects of licorice have been observed in humans.

some

Paul Grant & Shamin Ramasamy. 2012. An update on plant derived anti-androgens. International journal of endocrinology and metabolism 10(2), 497-502.

Licorice and its constituents/derivatives affect the cardiovascular system by disrupting hormones involved in water/salt balance.

some

Mikkel R. Deutch, Daniela Grimm, Markus Wehland, Manfred Infanger & Marcus Krüger. 2019. Bioactive Candy: Effects of Licorice on the Cardiovascular System. Foods (Basel, Switzerland) 8(10).

Licorice extracts impacted pituitary hormone secretion in vitro and in vivo in rats.

some

Ho Young Lee, Dae Young Jung, Hyekyung Ha, Sam Sik Kang, Ju Sun Kim & Chungsook Kim. 2007. Induction of growth hormone release by glycyrrhizae radix on rat. Journal of biochemistry and molecular biology 40(6), 979-85.

Licorice extract exhibits estrogenic activity in vitro.

some

D. T. Zava, M. Blen & G. Duwe. 1997. Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture. Environmental health perspectives 105 Suppl 3, 637-45.

Minor eye irritation observed in rabbits.

low

Cosmetic Ingredient Review (CIR): CIR Assessments

Mixed evience of minor skin irritation in humans. No evidence of skin irritation in animal testing.

low

Cosmetic Ingredient Review (CIR): CIR Assessments

No evidence of skin sensitization in human or animal testing.

low

Cosmetic Ingredient Review (CIR): CIR Assessments

Licorice-derived substances exhibit antioxidant properties in vitro.

low

Giulia Pastorino, Laura Cornara, Sónia Soares, Francisca Rodrigues & M. Beatriz P. P. Oliveira. 2018. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytotherapy research : PTR 32(12), 2323-2339.

Licorice may be prevent against liver damage caused by other agents.

low

Giulia Pastorino, Laura Cornara, Sónia Soares, Francisca Rodrigues & M. Beatriz P. P. Oliveira. 2018. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytotherapy research : PTR 32(12), 2323-2339.



Understanding scores

EWG provides information on cleaning product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.

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Hazard score

The Healthy Cleaning ingredient hazard score, from A to F, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

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