Structurally related substances are classified by IARC as known, probable, and possible human carcinogens (International Agency for Research on Carcinogens).
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
A review study found that cell-based screening tests suggest the potential for neurotoxicity.
Peer Reviewed Literature: Kobylewski, S. & Jacobson, M.F. 2012. Toxicology of food dyes. International journal of occupational and environmental health 18(3), 220-46.
A review study found that cell-based screening tests suggest the potential for neurotoxicity.
Peer Reviewed Literature: Kobylewski, S. & Jacobson, M.F. 2012. Toxicology of food dyes. International journal of occupational and environmental health 18(3), 220-46.
NTP Toxcast scored 2.5-3.5
National Toxicology Program (NTP): EWG Toxcast Analysis
NTP Toxcast scored 2.5-3.5
National Toxicology Program (NTP): EWG Toxcast Analysis
Neurobehavioral effects observed in animal study.
Toyohito Tanaka, Osamu Takahashi, Akiko Inomata, Akio Ogata & Dai Nakae. 2012. Reproductive and neurobehavioral effects of brilliant blue FCF in mice. Birth defects research. Part B, Developmental and reproductive toxicology 95(6), 395-409.
Concerns from impurities
Impurity: ANILINE
Suspected of causing genetic defects
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ANILINE
Suspected of causing cancer
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ANILINE
Causes damage to organs through prolonged or repeated exposure
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ANILINE
Known to cause cancer
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: CADMIUM
Suspected of causing genetic defects
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
May cause cancer
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Causes damage to organs through prolonged or repeated exposure
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging fertility.
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging the unborn child.
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Carcinogenic to humans
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: CADMIUM
Known To Be Human Carcinogen
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: ANILINE
Probably carcinogenic to humans
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: ANILINE
Probably carcinogenic to humans
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: CADMIUM
Probably carcinogenic to humans
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer